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. 2025 Jan 21;14(2):e240187. doi: 10.57264/cer-2024-0187

Table 6. . Unadjusted hazard ratios (ref = sertraline).

Drug Change HR (95% CI) Augmentation HR (95% CI) All hospitalization HR (95% CI)
Bupropion 1.05 (1.00, 1.11) 0.95 (0.92, 0.98) 0.67 (0.63, 0.72)
Citalopram 1.33 (1.28, 1.38) 1.23 (1.20, 1.26) 1.11 (1.06, 1.16)
Duloxetine 0.81 (0.77, 0.85) 0.76 (0.73, 0.78) 0.95 (0.90, 1.00)
Escitalopram 0.94 (0.90, 0.99) 0.92 (0.89, 0.95) 0.78 (0.74, 0.83)
Fluoxetine 0.99 (0.93, 1.04) 1.03 (0.99, 1.06) 0.86 (0.81, 0.93)
Mirtazapine 1.29 (1.24, 1.35) 1.20 (1.17, 1.23) 1.60 (1.53, 1.67)
Paroxetine 1.24 (1.17, 1.32) 1.24 (1.19, 1.29) 0.82 (0.76, 0.89)
Venlafaxine 1.07 (1.02, 1.14) 1.20 (1.16, 1.24) 0.83 (0.77, 0.89)

Indicates statistical significance.

CI: Confidence interval; HR: Hazard ratio.