Table 1.
Effects of baseline TLR expression and invasion status on cytokine responsiveness (ΔIL-1β and ΔIL-10) in house sparrows.
|
dependent variable: ▲ IL-1β | |||||
|---|---|---|---|---|---|
|
fixed effects |
estimate ± SE |
t-value |
p‐value |
variance |
s.d. |
|
intercept |
0.165 ± 0.343 |
0.481 |
0.631 |
||
|
TLR2 |
−0.091 ± 0.170 |
−0.531 |
0.595 |
||
|
status (non-native) |
0.692 ± 0.534 |
1.296 |
0.195 |
||
|
TLR4 |
−0.085 ± 0.200 |
−0.424 |
0.671 |
||
|
status × TLR2 |
0.117 ± 0.243 |
0.481 |
0.631 |
||
|
status × TLR4 |
-0.735 ± 0.293 |
-2.504 |
0.012 |
||
|
country |
0.079 |
0.282 |
|||
|
marginal R2 = 0.21; conditional R2= 0.15 | |||||
|
dependent variable: ▲ IL-10 | |||||
|---|---|---|---|---|---|
|
fixed effects |
estimate ± SE |
t-value |
p‐value |
variance |
s.d. |
|
intercept |
0.324 ± 0.348 |
0.929 |
0.353 |
||
|
TLR2 |
−0.297 ± 0.173 |
−1.712 |
0.087 |
||
|
status (non-native) |
0.476 ± 0.542 |
0.878 |
0.380 |
||
|
TLR4 |
−0.033 ± 0.203 |
−0.161 |
0.872 |
||
|
status × TLR2 |
0.227 ± 0.247 |
0.920 |
0.358 |
||
|
status × TLR4 |
−0.623 ± 0.298 |
−2.089 |
0.037 |
||
|
country |
0.081 |
0.285 |
|||
|
marginal R2 = 0.19; conditional R2 = 0.13 | |||||
|
Linear mixed model results exploring the impact of TLR-2 and TLR-4 (surveillance molecules) on cytokine responsiveness (ΔIL-1β and ΔIL-10), along with the interaction between these molecules and invasion status (native versus non-native). Notably, the model included country as a random fixed effect and variables with p values less than 0.05 are bolded in the table. | |||||