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. 2025 Jan 29;21(1):20240431. doi: 10.1098/rsbl.2024.0431

Table 1.

Effects of baseline TLR expression and invasion status on cytokine responsiveness (ΔIL-1β and ΔIL-10) in house sparrows.

dependent variable: ▲ IL-1β

fixed effects

estimate ± SE

t-value

p‐value

variance

s.d.

intercept

0.165 ± 0.343

0.481

0.631

TLR2

−0.091 ± 0.170

−0.531

0.595

status (non-native)

0.692 ± 0.534

1.296

0.195

TLR4

−0.085 ± 0.200

−0.424

0.671

status × TLR2

0.117 ± 0.243

0.481

0.631

status × TLR4

-0.735 ± 0.293

-2.504

0.012

country

0.079

0.282

marginal R2 = 0.21; conditional R2= 0.15

dependent variable: ▲ IL-10

fixed effects

estimate ± SE

t-value

p‐value

variance

s.d.

intercept

0.324 ± 0.348

0.929

0.353

TLR2

−0.297 ± 0.173

−1.712

0.087

status (non-native)

0.476 ± 0.542

0.878

0.380

TLR4

−0.033 ± 0.203

−0.161

0.872

status × TLR2

0.227 ± 0.247

0.920

0.358

status × TLR4

−0.623 ± 0.298

−2.089

0.037

country

0.081

0.285

marginal R2 = 0.19; conditional R2 = 0.13

Linear mixed model results exploring the impact of TLR-2 and TLR-4 (surveillance molecules) on cytokine responsiveness (ΔIL-1β and ΔIL-10), along with the interaction between these molecules and invasion status (native versus non-native). Notably, the model included country as a random fixed effect and variables with p values less than 0.05 are bolded in the table.