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. 2025 Feb;69(2):204–215. doi: 10.1016/j.jpainsymman.2024.10.026

Table 2.

Morphine Equivalents Requirements in mg for SHS by Condition and Age Group According to Estimated Intensity and Duration of Symptoms

ICD 10 Conditions Decedents
Non-Decedents
All ages Under 5 5- 19 +20 All ages Under 5 5- 19 +20
A96,98,99 Hemorrhagic fevers 80 80
A15-19 TB deaths from M/XDR TB 264 90
A15-19 TB deaths from regular TB 42
B20-24 HIV disease 675 150
C00-97 (except C91-95) Malignant neoplasms 9000 480
C91-95 Leukemia 990 1393 4162 480
F00-04 Dementia 270 10
G00-09 Inflammatory disease of the central nervous system 160 160 (TN)
G20-26; G30-32; G35-37; G40-41; G80-83 Degenerative disease of central nervous system 288 30 (PD); 80 (MS)
I60-69 Cerebrovascular disease 180 10
I05-09; I25; I42 & I50 Chronic rheumatic heart disease; cardiomyopathy & heart failure 480
I25 Chronic ischemic heart disease 540
J40-47; J60-70; J80-84; J95-99 Lung disease 540
K70-77 Diseases of liver 270 744 2218 2190
N17-19 Renal failure 270 706 2143 1460
P07; P10-15 Low birth weight & prematurity; Birth trauma 42 553 (PT)
2514(BT)
6668 (BT)
Q00-99 Congenital malformations 84 24
S00-99; T00-98; V01-Y98 Injury, poisoning, external causes 400 400
I70 Atherosclerosis 1980
M00-97: Musculoskeletal disorders 396 396
E40-46 Protein-Energy Malnutrition 4
D50-89, E00-89 Endocrine, Metabolic, Blood and Immune Disorders 504 (DM);
668 (T);
1823 (SC)
1391 (DM);
6536 (T);
10365 (SC)
2520 (SC) 351 (T); 972 (SC) 1651 (T); 4651 (SC) 2520 (SC)

TN: Tetanus; PD = Parkinson's disease; MS = multiple sclerosis; PT = preterm birth; BT = birth asphyxia and birth trauma complications; DM = Diabetes Mellitus; T = Thalassemias; SC = Sickle cell disorders.