Figure 3.

Male, but not female, rats are sensitive to pavlovian outcome devaluation, and this sensitivity is blocked by intra-DMS rimonabant regardless of the tracking group. Data represented as within-subject individual data (lines) and group data (bars; mean ± SEM). A, B, In ST rats, we observe a significant outcome value × treatment × sex interaction on total behavior. In male ST rats, we observed a significant outcome value × treatment interaction. Post hocs confirm that male ST rats were sensitive to devaluation with lower responding for devalued relative to valued conditions, while all other post hocs were not significant. C, D, In GT/INT rats, we observed an outcome value × treatment interaction, but no interaction with sex. Post hoc comparisons: ^#p = 0.055, **p < 0.025. See Extended Data Figure 3-1 for an analysis of lever contacts and Extended Data Figure 3-2 for an analysis of food cup contacts.