Figure 6.

Activation of CB1R by WIN reduces sIPSC frequency and increases sIPSC interevent interval, regardless of sex. A, Representative sIPSC traces from DMS cells pre- (blue) and post-WIN (light blue) bath application from Long Evans rats (1–2 cells per rat; n = 21 cells). Scale bars: 20 pA and 1 s. Data presented as mean ± SEM. B, Mean amplitude with individual data for males (blue lines) and females (purple lines). C, Mean frequency with individual data for males and females. D, Cumulative frequency of interevent interval of sIPSCs. **p < 0.025.