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The factors influencing endothelial glycocalyx degradation. TNFα, tumor necrosis factor; NF-κB, nuclear factor kappa-B; P38MAPK, p38 mitogen-activated protein kinase; HBP, high blood pressure; AGEs, advanced glycation end-products; RAGE, receptor of advanced glycation end-products; ROS, reactive oxygen species; HDAC, histone deacetylase; ANGPT2, Angiopoietin-2; NADPH, nicotinamide adenine dinucleotide phosphate; CPB, cardiopulmonary bypass. (By Figdraw).
