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. 2025 Jan 16;14:1496176. doi: 10.3389/fcimb.2024.1496176

Table 3.

Mortality data of study population by treatment allocation.

Control
N=139
LPV/r
N=139
Difference Adj.p (vs. control) DRV/r
N=139
Difference Adj.p (vs. control) LPV/r
vs. DRV/r
difference
Adj.p
LPV/r vs. DRV/r
Days spent in hospital 8.09 ± 6.0 10.63 ± 5.5 -2.54 (-4.24 to -0.83) <0.001 12.83 ± 6.4 -4.73(-6.42 to -3.044) <0.001 -2.193 (-3.89 to -0.48) 0.007
Time to clinical improvement
(average days ± SD)
7.9 ± 5.9 10.6 ± 5.4 -2.69 (-4.41 to -0.97) <0.001 11 ± 6.3 -3.13 (-4.87 to -1.37) <0.001 -0.43 (-2.16 to 1.30) 0.82
In-hospital mortality 10 (7.2%) 5 (3.6%) 0.09 14 (10%) 0.19 0.016
Time to death 10.1 ± 6.7 13.8 ± 8.4 -3.7 (-13.68 to 6.27 0.63 13.4 ± 7.1 -3.32 (-10.87 to 4.21) 0.52 0.37 (-9.11 to 9.8) 0.99
Univariate analysis (HR, 95% CI) 0.39 (0.19-0.99) 0.04 1.49 (0.71-3.12) 0.28

Data is expressed as mean ± SD. CI, confidence interval; HR, hazard ratio.