Table 3.
Mortality data of study population by treatment allocation.
Control N=139 |
LPV/r N=139 |
Difference | Adj.p (vs. control) | DRV/r N=139 |
Difference | Adj.p (vs. control) | LPV/r vs. DRV/r difference |
Adj.p LPV/r vs. DRV/r |
|
---|---|---|---|---|---|---|---|---|---|
Days spent in hospital | 8.09 ± 6.0 | 10.63 ± 5.5 | -2.54 (-4.24 to -0.83) | <0.001 | 12.83 ± 6.4 | -4.73(-6.42 to -3.044) | <0.001 | -2.193 (-3.89 to -0.48) | 0.007 |
Time to clinical improvement (average days ± SD) |
7.9 ± 5.9 | 10.6 ± 5.4 | -2.69 (-4.41 to -0.97) | <0.001 | 11 ± 6.3 | -3.13 (-4.87 to -1.37) | <0.001 | -0.43 (-2.16 to 1.30) | 0.82 |
In-hospital mortality | 10 (7.2%) | 5 (3.6%) | 0.09 | 14 (10%) | 0.19 | 0.016 | |||
Time to death | 10.1 ± 6.7 | 13.8 ± 8.4 | -3.7 (-13.68 to 6.27 | 0.63 | 13.4 ± 7.1 | -3.32 (-10.87 to 4.21) | 0.52 | 0.37 (-9.11 to 9.8) | 0.99 |
Univariate analysis (HR, 95% CI) | – | 0.39 (0.19-0.99) | – | 0.04 | 1.49 (0.71-3.12) | – | 0.28 |
Data is expressed as mean ± SD. CI, confidence interval; HR, hazard ratio.