Table 4.
Hazard ratios for the risk factor of death in the study population.
| HR | CI 95% | p value | |
|---|---|---|---|
| Age | 1.04 | 1.00-1.07 | 0.02 |
| Male sex | 3.63 | 1.23-10.68 | 0.02 |
| LPV/r | 0.25 | 0.09-0.66 | <0.01 |
| DRV/r | 2.60 | 1.37-4.92 | <0.01 |
| Obesity | 1.49 | 0.65-3.43 | 0.34 |
| Diabetes | 2.49 | 1.05-5.58 | 0.03 |
| Low SaO2 (<90%) | 5.23 | 2.45-11.17 | <0.001 |
| High glucose >125 mg/dl | 3.68 | 1.23-10.91 | 0.01 |
| Grade1 lesion (<25%) | 0.12 | 0.02-0.53 | 0.005 |
| Grade3 lesion (>50%) | 2.67 | 1.12-6.39 | 0.03 |
| Dexamethasone | 1.69 | 0.55-5.18 | 0.36 |
| Oxygen therapy | 1.37 | 0.57-3.31 | 0.47 |
Cox proportional hazard model was used to determine the relationship of clinical factors and in-hospital mortality in the treated and control groups (n=417). Hazard ratios are shown with 95% CIs. All COVID-19 hospitalised patients underwent a chest CT scan and the extension of lung lesions was graded as mild (<25%, Grade 1), moderate (25-50%, Grade 2) or severe (>50%, Grade 3).