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Improvement in function assignment accuracy of iCSA compared with sequence homology alone. (a) Results are shown for the accuracy of EC assignment to Swiss-Prot homologues obtained by using the iCSA filter (black bars) and compared, at each psi-blast iteration up to four, with results obtained by using just psi-blast (gray bars). (b) Percentage improvement in function assignment accuracy with iCSA compared with psi-blast only.
