Table 3.

Comparison of pubertal data by genotype (PTPN11 vs SHOC2 patients).

PUBERTAL CLINICAL PARAMETERS	PTPN11 (n=25) Median [IQR]	SHOC2 (n=7) Median [IQR]	p-value
Age at puberty onset (yrs)	12.33 [11.32-13.25]	12.73 [11.42-14.07]	0.469
Height at puberty (cm)	135.55 [131.95-140.8]	133.9 [129.5-143.5]	0.686
Spurt duration (yrs)	6.64 [5.43-7.75]	5.665 [3.23-7.995]	0.764
PHV (cm)	7.86 [6.60-8.33]	6.19 [5.43-6.34]	0.070
Spurt gain (cm)	20.6 [19.6-26.2]	14.25 [3.40-29.95]	0.531
Age at menarche (yrs)	14.45 [12.28-16.40]	19.4 [14.64-19.41]	0.066
Final height (cm)	159.3 [151.7-165.8]	149.5 [148.4-158.4]	0.256

PHV, peak of height velocity.