Table 2.

Pediatric T-cell lymphomas and relative frequency

Common

T-lymphoblastic lymphoma

Anaplastic large-cell lymphoma, ALK positive

Less common and rare

Subcutaneous panniculitis-like T-cell lymphoma

Hepatosplenic T-cell lymphoma

Mycosis fungoides

Primary cutaneous CD30 + lymphoproliferative disorders

Lymphomatoid papulosis

Primary cutaneous anaplastic large-cell lymphoma

Peripheral T-cell lymphoma, NOS

Anaplastic large-cell lymphoma, ALK negative

Extranodal NK/T-cell lymphoma

Primary cutaneous gamma-delta T-cell lymphoma

Very rare

EBV-positive lymphoproliferations of childhood

Severe mosquito bite allergy

Systemic chronic active EBV disease, systemic

Systemic EBV + T-cell lymphoma of childhood

Hydroa vacciniforme lymphoproliferative disorder

Aggressive NK-cell leukemia

Primary cutaneous CD4 + small/medium T-cell LPD

T-cell large granular lymphocytic leukemia

Enteropathy-associated T-cell lymphoma

Adult T-cell leukemia/lymphoma

Modified from [9, 13], underlined lymphoma are definitive subtypes in WHO Paediatric WHO Haematolymphoid disorders

LPD lymphoproliferative disorder, EBV Epstein-Barr virus, NOS not otherwise specified, NK natural killer cell, ALK anaplastic lymphoma kinase

Common, less common and rare, and very rare are terminology used by COG [9] but not defined. Common is rougly > 10% while very rare is < 1–2%