Table 5.
Worsening of Glycemic Control indicators
| Overall (n = 151) | Non-DM (n = 68) | DM (n = 83) | P value | |
|---|---|---|---|---|
| Hba1c at baseline, mean (SD) | 7.41 (± 2.09) | 5.68 (± 0.46) | 8.83 (± 1.81) | < 0.001** |
| Hba1c at follow-up, mean (SD) | 7.40 (± 2.15) | 5.72 (± 0.48) | 8.77 (± 2.01) | < 0.001** |
| Average change in Hba1c, mean (SD) | 0.01 (± 1.29) | −0.04 (± 0.32) | 0.06 (± 1.72) | 0.585** |
| Worsening of glycemic control (change in Hba1c by more than 0.5), n (%) | 36 (23.8) | 10 (14.7) | 26 (31.3) | 0.017 |
| Onset from baseline in months, Mean (SD) | 11.76 (± 6.66) | 13.07 (± 7.18) | 11.26 (± 6.53) | 0.473** |
| New onset of diabetes, n (%) | 5 (3.3) | 5 (7.35) | 0 (0.06) | |
| Onset from baseline in months, mean (SD) | 15.73 (± 9.78) | 15.6 (± 10.57) | – | – |
| Insulin use at baseline, n (%) | 50 (33.1) | 0 (0.0) | 50 (60.2) | < 0.001 |
| Insulin initiated during follow-up, n (%) | 6 (4.0) | 0 (0.0) | 6 (7.2) | 0.033 * |
| Number of diabetes medications used at baseline, mean (SD) | 1.23 (± 1.24) | 0.13 (± 0.38) | 2.12 (± 0.94) | < 0.001** |
| Number of diabetes medications used by end of follow-up, mean (SD) | 1.51 (± 1.39) | 0.31 (± 0.55) | 2.49 (± 1.06) | < 0.001** |
DM: diabetes mellitus; NDM: none diabetes mellitus
*Fisher’s Exact
**Student -t test, all others were Chi-square test