Table 1.
Antimicrobial activity of compounds 9–32 expressed as diameters of inhibition zone (mm)
| Compound | Gram positive bacteria | Gram negative bacteria | Fungi | |||
|---|---|---|---|---|---|---|
| Number | S. aureus ATCC 6538 | B. subtilis ATCC 6633 | B. cereus ATCC 6629 | K. pneumoniae ATCC 13883 | P. aeruginosa ATCC 27953 | C. albicans ATCC 10231 |
| 9 | – | 15 ± 0.25 | 14 ± 0.09 | 12 ± 0.17 | 21 ± 0.36 | – |
| 10 | – | – | – | 15 ± 0.15 | – | – |
| 11 | – | 14 ± 0.16 | – | – | – | – |
| 12 | – | – | – | – | 18 ± 0.27 | – |
| 13 | – | – | – | 12 ± 0.07 | 20 ± 0.18 | 12 ± 0.28 |
| 14 | – | – | – | – | – | 12 ± 0.37 |
| 15 | 12 ± 0.26 | 10 ± 0.33 | – | 13 ± 0.41 | – | 11 ± 0.11 |
| 16 | 12 ± 0.08 | – | 13 ± 0.14 | – | 17 ± 0.26 | 13 ± 0.29 |
| 17 | – | – | – | – | 16 ± 0.22 | – |
| 18 | 14 ± 0.21 | 16 ± 0.31 | 17 ± 0.30 | 18 ± 0.20 | – | 13 ± 0.14 |
| 19 | – | 14 ± 0.31 | 17 ± 0.22 | 18 ± 0.24 | 16 ± 0.18 | – |
| 20 | 13 ± 0.11 | 10 ± 0.12 | 16 ± 0.07 | 16 ± 0.09 | 21 ± 0.17 | – |
| 21 | – | 17 ± 0.14 | 12 ± 0.16 | 12 ± 0.15 | – | – |
| 22 | – | 10 ± 0.07 | – | – | – | – |
| 23 | – | – | – | – | – | 11 ± 0.13 |
| 24 | – | – | – | 12 ± 0.14 | 14 ± 0.21 | – |
| 25 | – | – | – | 14 ± 0.17 | 21 ± 0.17 | – |
| 26 | – | 12 ± 0.11 | – | 11 ± 0.07 | – | – |
| 27 | – | 14 ± 0.15 | – | 14 ± 0.16 | – | 13 ± 0.09 |
| 28 | – | 12 ± 0.20 | – | 16 ± 0.18 | – | – |
| 29 | – | 14 ± 0.06 | – | 20 ± 0.15 | 14 ± 0.16 | 13 ± 0.07 |
| 30 | 12 ± 0.12 | – | – | 14 ± 0.15 | – | – |
| 31 | – | – | – | – | – | – |
| 32 | – | 14 ± 0.27 | – | – | 18 ± 0.09 | – |
| Ciprofloxacin | 23 ± 0.15 | 33 ± 0.20 | 29 ± 0.18 | 26 ± 0.17 | 35 ± 0.28 | – |
| Fluconazole | – | – | – | – | – | 20 ± 0.18 |