Figure 4.

Antipsychotic physiological effects relative to placebo

Antipsychotic drugs in this Kilim plot are ranked by mean difference (95% CI) for each variable except QTc, for which data are standardised mean difference (95% CI). Colours correspond to the strength of the statistical evidence supporting the relative effects of a drug versus placebo. For example, deep green indicates strong evidence that a drug is associated with an improvement in that variable compared with placebo (which, for all variables except HDL cholesterol, means a reduction in that variable). Conversely, deep red indicates strong evidence that the drug is associated with a worsening in that variable compared with placebo (which, for all variables except for HDL cholesterol, means an increase in that variable). Colours close to white indicate little evidence on whether the drug performs better or worse than placebo. QTc=heart rate-corrected QT interval.