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. Author manuscript; available in PMC: 2025 Feb 4.
Published in final edited form as: Curr Top Microbiol Immunol. 2019;420:211–231. doi: 10.1007/82_2018_137

Fig. 5.

Fig. 5

Different small molecules access different regions of the NAD+ binding pocket. a PARP1 in complex with niraparib (PDB 4R6E); b PARP1 in complex with rucaparib (PDB 4RV6); b PARP2 in complex with olaparib (PDB 4TVJ); d PARP5b in complex with EB-47 (PDB 4TK5); e PARP5b in complex with IWR-1-endo (PDB 3UA9); f PARP5b in complex with G007-LK; g PARP10 in complex with 3-aminobenzamide (PDB 3HKV); h PARP14 in complex with 3-aminobenzamide (PDB 3GOY); i PARP14 in complex with compound 4s (PDB 5NQE)