Table 3. Uni- and multivariable logistic regression analysis in the prediction of non-response group in ANPC patients.
Predictors | Univariable analysis | Multivariable analysis* | |||||
---|---|---|---|---|---|---|---|
OR | 95% CI | P | OR | 95% CI | P | ||
T1, ms | 0.99 | 0.98–1.00 | <0.001 | 0.99 | 0.98–1.00 | 0.031 | |
T2, ms | 0.94 | 0.89–0.99 | 0.046 | 1.11 | 0.98–1.25 | 0.097 | |
PD, pu | 0.67 | 0.54–0.84 | <0.001 | 0.65 | 0.47–0.91 | 0.011 | |
ADC, ×10-6 mm2/s | 1.00 | 0.99–1.00 | 0.092 | ||||
EBV-DNA | |||||||
<4000 | Reference | Reference | |||||
≥4000 | 4.28 | 1.51–12.18 | 0.006 | 25.21 | 2.73–231.90 | 0.004 | |
Extranodal extension | |||||||
No | Reference | Reference | |||||
Yes | 4.68 | 1.66–13.24 | 0.004 | 3.95 | 0.68–22.86 | 0.125 | |
Clinical stage | |||||||
III | Reference | Reference | |||||
IV | 5.53 | 1.93–15.82 | 0.002 | 6.72 | 1.11–40.63 | 0.037 | |
Ki-67 expression | |||||||
Low | Reference | Reference | |||||
High | 10.88 | 3.42–36.62 | <0.001 | 7.39 | 1.04–50.32 | 0.045 |
*Variable with P < 0.05 at univariable analysis were included in the multivariable analysis.
ANPC = advanced nasopharyngeal carcinoma, OR = odds ratio, CI = confidence interval, T1 = longitudinal relaxation time, T2 = transverse relaxation time, PD = proton density, pu = percentage unit, ADC = apparent diffusion coefficient, EBV = Epstein–Barr virus