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. 2025 Jan 22;16:1465657. doi: 10.3389/fphar.2025.1465657

TABLE 3.

Sensitivity analysis of the relationship between β-blockers use and 28-day mortality.

Variable Crude HR (95%CI) P value Adjusted HR (95%CI) a P value
Non-CHF and Non- hypertension 0.46 (0.28–0.78) 0.003 0.35 (0.20–0.61) <0.001
Metoprolol 0.64 (0.46–0.89) 0.008 0.49 (0.34–0.68) <0.001
Other type β-blockers 0.21 (0.07–0.66) 0.007 0.26 (0.07–0.91) 0.0036
Oral administration 0.41 (0.27–0.61) <0.001 0.39 (0.25–0.61) <0.001
Intravenous administration 0.77 (0.50–1.16) 0.212 0.48 (0.31–0.75) 0.001
a

Multivariate COX, model adjusted for confounders.

Confounding variables are those listed in Supplementary Table S4 that have a P value of less than 0.05. HR, hazard ratio; 95% CI, 95% confidence interval.