Table 3. Parameters for the Interaction of Different CAIs with Human Carbonic Anhydrase II.

CAI	ka (106 M–1 s–1)	kd (10–2 s–1)	KD (nM)
A01	0.57 ± 0.33	1.45 ± 0.15	36.90 ± 23.39
A05	0.61 ± 0.25	1.70 ± 0.25	31.50 ± 9.19
A07	0.24 ± 0.05	1.78 ± 0.40	75.57 ± 11.22
A15	0.43 ± 0.25	1.25 ± 0.43	46.00 ± 29.81
A17	0.13 ± 0.05	1.27 ± 0.11	113.30 ± 50.67
A19	0.15 ± 0.04	2.25 ± 0.02	161.33 ± 40.96
acetazolamide	1.04 ± 0.46 × 106	1.24 ± 0.47 × 10–2	13.15 ± 3.44
dorzolamide	1.18 ± 0.62 × 106	0.56 ± 0.12 × 10–2	6.64 ± 3.86