Table 4.
Correlation between EGFR mutation and RASSF1A and SHOX2 methylations
| Methylation | EGFR mutation | P value (Chi-square) | Rho (Spearman) | P value (Correlation) | P value (CMH test) | ||
|---|---|---|---|---|---|---|---|
| Mutated (%) | Wild type (%) | ||||||
| RASSF1A | + | 42 (53.2) | 37 (46.8) | 0.002 | 0.196 | 0.002 | 0.038 |
| − | 58 (32.4) | 121 (67.6) | |||||
| SHOX2 | + | 26 (42.6) | 35 (57.4) | 0.478 | 0.044 | 0.480 | 0.576 |
| − | 74 (37.6) | 123 (62.4) | |||||
Cochran–Mantel–Haenszel test was used for the correlation analysis after controlling the pathological subtypes as covariates