. 2023 Apr 25;149(11):8557–8571. doi: 10.1007/s00432-023-04745-8

Table 5.

Correlation and consistency between EGFR mutation and RASSF1A methylations in different pathological groups

	RASSF1A methylation	EGFR		P value (McNemar)	Rho (Spearman)	P value (Correlation)	Kappa	P value (Kappa)
	RASSF1A methylation	Mutated (%)	Wild type (%)	P value (McNemar)	Rho (Spearman)	P value (Correlation)	Kappa	P value (Kappa)
Noninvasive	+	13 (65.0)	7 (35.0)	0.013	0.371	< 0.001	0.351	< 0.001
Noninvasive	−	21 (20.0)	84 (80.0)	0.013	0.371	< 0.001	0.351	< 0.001
Invasive	+	29 (49.2)	30 (50.8)	0.464	− 0.008	0.923	− 0.008	0.923
Invasive	−	37 (50.0)	37 (50.0)	0.464	− 0.008	0.923	− 0.008	0.923

McNemar test: paired-sample Chi-square test was used for the comparisons between two assays in different groups