Table 4.
Postoperative complications and drug-related adverse effects in the two groups
| SSA group (n = 61) | Control group (n = 62) | Absolute difference (95% CI) | P | |
|---|---|---|---|---|
| Total numbera (n, %) | 6 (9.8) | 15 (24.2) | 14.4 (1.3–27.4) | 0.034* |
| Grade B and C POPFb (n, %) | 0 (0) | 3 (4.8) | 4.8 (− 0.5–10.2) | 0.248** |
| Anastomotic leakage (n, %) | 0 (0) | 1 (1.6) | 1.6 (− 1.5–4.8) | 1.000*** |
| Chylous fistula (n, %) | 2 (3.3) | 0 (0) | − 3.3 (− 7.8–1.2) | 0.244*** |
| Intra-abdominal infection (n, %) | 1 (1.6) | 5 (8.1) | 6.4 (− 1.1–13.9) | 0.217** |
| Intraluminal bleeding (n, %) | 1 (1.6) | 0 (0) | − 1.6 (− 4.8–1.6) | 0.496*** |
| Intra-abdominal bleeding (n, %) | 1 (1.6) | 2 (3.2) | 1.6 (− 3.8–7.0) | 1.000** |
| Ileus (n, %) | 0 (0) | 3 (4.8) | 4.8 (− 0.5–10.2) | 0.248** |
| Abdominal effusion/abscess (n, %) | 2 (3.3) | 4 (6.5) | 3.2 (− 4.4–10.8) | 0.690** |
| Pneumonia (n, %) | 1 (1.6) | 3 (4.8) | 3.2 (− 3.0–9.4) | 0.623** |
| Clavien–Dindo classification (n, %) | 0.210*** | |||
| I | 2 (3.3) | 2 (3.2) | − 0.1 (− 6.3–6.2) | |
| II | 2 (3.3) | 8 (12.9) | 9.6 (0.2–19.1) | |
| III | 1 (1.6) | 2 (3.2) | 1.6 (− 3.8–7.0) | |
| IV | 1 (1.6) | 3 (4.8) | 3.2 (− 3.0–9.4) | |
| V | 0 (0) | 0 (0) | 0.0 (0.0–0.0) | |
| Readmission | 1 (1.6) | 5 (8.1) | 6.4 (1.1–13.9) | 0.217** |
| Drug-related adverse effectc (n, %) | 2 (3.3) | 0 (0) | − 3.3 (− 7.8–1.2) | 0.244*** |
SSA somatostatin analog, POPF postoperative pancreatic fistula
aThere were 8 complications in 6 patients in the SSA group and 21complications in 15 patients in the control group
bGrade A POPF is not an actual postoperative complication according to ISGPF criteria
cTwo patients in the SSA group had drug-related adverse effects, manifested as mild nausea during the intervention
*Chi-squared test
**Adjusted chi-squared test
***Fisher’s exact test