Figure 2.

Effects of 1 mm Na⁺ on K⁺, Rb⁺, Li⁺, and Cs⁺ in EcHKT1- and EcHKT2-expressing and uninjected X. laevis oocytes. Current traces recorded at −120 mV from an uninjected (A), EcHKT1-expressing (B), and EcHKT2-expressing (C) oocyte. Traces with K⁺ and Na⁺ in bath have been labeled and the rest are traces with Rb⁺, Li⁺, and Cs⁺ that correspond to histograms. Current changes (D and E) measured in EcHKT1(n = 4 oocytes), EcHKT2 (n = 4), and uninjected oocytes (n = 4) in the presence of 1 mm Na⁺ plus 10 mm X ion in bath solution. Current difference (Δ current) is the difference between the currents recorded at 0 mm monovalent cations and 1 mm Na⁺/10 mm X ion.