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. Author manuscript; available in PMC: 2025 Feb 5.
Published in final edited form as: Psychol Med. 2023 Jan 5;54(1):108–116. doi: 10.1017/S0033291722003555

Table 4.

Analyses of inflammation as a meditator of the relationship change in HAM-D scores and change in regional brain volume HAM-D change as dependent variable

Without IL-8
With IL-8
Predictors Coeff t p Coeff t p

Cluster 2 volume change 134.2 2.63 0.02 113.3 2.55 0.03

IL-8 change 15.7 3.17 0.01

All variables were corrected as described in the main text. Interaction terms were not significant and removed from the final regression equation.