Table 4.
Analyses of inflammation as a meditator of the relationship change in HAM-D scores and change in regional brain volume HAM-D change as dependent variable
|
Without IL-8
|
With IL-8
|
|||||
|---|---|---|---|---|---|---|
| Predictors | Coeff | t | p | Coeff | t | p |
|
| ||||||
| Cluster 2 volume change | 134.2 | 2.63 | 0.02 | 113.3 | 2.55 | 0.03 |
|
| ||||||
| IL-8 change | – | – | – | 15.7 | 3.17 | 0.01 |
All variables were corrected as described in the main text. Interaction terms were not significant and removed from the final regression equation.