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. 2025 Jan 9;40(1):27–42. doi: 10.1007/s10654-024-01188-4

Table 2.

Characteristics of the histopathologically confirmed distant metastases of the cases of the discovery set

n (%)
Number of histopathologically confirmed metastases per patient
01 71 (32)
1 113 (51)
 > 1 17 (8)
Localization histopathologically confirmed distant metastasis2
Lymph node (distant) 15 (15)
Lung 15 (15)
Gastro-intestinal tract 15 (15)
Brains 10 (10)
Bone 6 (6)
Liver 11 (11)
Skin 13 (13)
Other 12 (12)
Total 97 (100)

1These patients had non-histologically confirmed metastasis (e.g. confirmed by imaging)

2Multiple histopathologically confirmed distant metastasis per patient have been included