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. 2002 Aug;1(4):643–652. doi: 10.1128/EC.1.4.643-652.2002

FIG. 4.

FIG. 4.

Two possible routes by which the ABCG genes may have arisen. It has been assumed that the original gene in which the ABC domain precedes the TM domain was formed by the fusion of independent regions encoding such domains. Alternatively, a copy of the central region of a preexisting ABC gene could have generated a functional half-transporter. Tandem duplication and fusion of this gene could have generated the full transporters.

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