Table 3.

Treatment-related adverse events

	All grades		Grade 3
	No.	%	No.	%
Hematologic
Anemia	19	63.3	1	3.3
Neutropenia	18	60.0	10	33.3
Leukopenia	9	30.0	6	20.0
Thrombocytopenia	3	10.0	2	6.7
Non-hematologic
Diarrhea	11	36.7	0	0.0
Creatinine elevation	6	20.0	0	0.0
Neuropathy	6	20.0	0	0.0
Rash	5	16.7	0	0.0
General weakness	5	16.7	0	0.0
Nausea	4	13.3	0	0.0
Edema	4	13.3	0	0.0
Anorexia	4	13.3	0	0.0
Abdominal pain	3	10.0	0	0.0
Dyspnea	2	6.7	0	0.0
Infection	2	6.7	0	0.0
ALP elevation	2	6.7	0	0.0
Cough	2	6.7	0	0.0
Constipation	2	6.7	0	0.0
AST elevation	2	6.7	1	3.3
Pneumonitis	2	6.7	0	0.0
Vomiting	2	6.7	0	0.0
Dyspepsia	2	6.7	0	0.0
Heartburn	2	6.7	0	0.0
Urine discoloration	2	6.7	0	0.0
Tumor necrosis	1	3.3	1	3.3
Pruritus	1	3.3	0	0.0
ALT elevation	1	3.3	0	0.0
Back pain	1	3.3	0	0.0
Hypertension	1	3.3	0	0.0
Mucositis/stomatitis	1	3.3	0	0.0
Asthenia	1	3.3	0	0.0
Paronychia	1	3.3	0	0.0
Fever	1	3.3	0	0.0
Pneumothorax	1	3.3	0	0.0
Hemorrhoid	1	3.3	0	0.0

ALP, alkaline phosphatase.