Table 2.
Treatment characteristics and response (n = 11)
Patients | Induction phase | Consolidation phase | Relapse | Survival | |||
---|---|---|---|---|---|---|---|
Regimen | Response | Regimen | Response | mo | mo | Status | |
1 | CHOP | Failure | – | – | – | 3 | DOD |
2 | CHOP | Failure | – | – | – | 2 | DOD |
3 | CHOP–bortezomib | PR | CT+ RT | PR | 20 | 48 | Alive |
4 | CHOP–bortezomib | Failure | – | – | – | 8 | DOD |
5 | CHOP– Chidamide | CR | AlloHCT | CR | – | 10 | Alive |
6 | GDP | PR | CT | Failure | – | 10 | DOD |
7 | IVAC | CR | CT | CR | 21 | 25 | Alive |
8 | VDCLP | PR | AlloHCT | CR | – | 27 | Alive |
9 | Hyper-CVAD | SD | AlloHCT | CR | 10 | 11 | DOD |
10 | DEP | Failure | – | – | – | 3 | DOD |
11 | DHAP | CR | AlloHCT | CR | – | 12 | Alive |
DOD died of disease, CR complete remission, PR partial remission, SD stable disease, CT chemotherapy, RT radiotherapy, CHOP cyclophosphamide, doxorubicin, vincristine, prednisone, GDP gemcitabine, cisplatin, dexamethasone, VDCLP vincristine, doxorubicin, cyclophosphamide, l-asparaginase, prednisone, Hyper-CVAD cyclophosphamide, vincristine, doxorubicin, dexamethasone, methotrexate, cytarabine, AlloHCT allogeneic hematopoietic cell transplantation, DEP dexamethasone, etoposide, doxorubicin, DHAP dexamethasone, cisplatin, cytarabine