Table 1.

Clinical and Molecular Data Related to Patients with WHS and Microdeletions^[Note]

Patientand Sex	Age atDelivery(wk)	BirthWeight(g)	Age atExamination(years)	GrowthDelay	CharacteristicFace	MR	Seizures	Microcephaly	CleftPalate	Age at LanguageAcquisition, Walking(mo)a	DeletionSize(Mb)
43, F	38	2,075	1	+	+	+	+b	+	+	N/A	3.5c
44, M	40	2,430	11	+	+	+	+	+	−	N/A	3.5
13, M	40	2,230	12	+	+	+	+	+	−	20	2.6
46, F	40	2,650	1	+	+	+	+	+	+	N/A	2.6
14, M	40	2,600	10	+	+	+	+	+	−	28	2.5d
26, F	39	2,600	7	+	+	+	+	+	−	48	2.5
15, F	40	2,600	10	+	+	+	+	−	−	60	2.2
MG, M	40	2,500	1	+	+	+	+	−	−	N/A	1.9

Note.— Patients are listed according to the extent of the deletion.

^aN/A = not available because of very early age at examination.

^bElectroencephalographic anomalies.

^cder(4)(pter→p16.3:10p15.3→pter).

^d+ dup(4)(p16.1p16.3).