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Haplotype analysis of the consanguineous pedigree with the shortest region of homozygosity. Informative markers and haplotypes are shown from telomere to centromere beneath the affected individual and her parents, showing the region of homozygosity between D4S2375 and D4S2935. Analysis of the other six pedigrees places the centromeric limit for the gene locus at 164F16P2 (data not shown). The gene order between D4S2375 and 164F16P2 is also shown.
