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. 2025 Jan 24;11:1507278. doi: 10.3389/fmed.2024.1507278

Table 3.

Diagnostic criteria for ischemic cardiovascular and cerebrovascular diseases with stasis and toxicity interaction.

Evaluation indicators Evaluation entries
Required indicators
  1. Persistent, refractory pain or consciousness disorders, accompanied by a rapid and deteriorating clinical course

  2. Radiographic findings demonstrate numerous ischemic events or significant vascular lesions, characterized by luminal stenosis of 70% or greater.

Main macro-indicators
  1. Purple tongue or dark purple tongue

  2. Sublingual vessel purplish-red or Dark purple

  3. Tongue with petechiae or ecchymosis

Secondary macro- indicators
  1. Foul or bitter taste in the mouth.

  2. Yellow and dry or yellow and greasy tongue coating.

  3. Tough tongue

  4. Uneven or wiry pulse.

Laboratory indicators
  1. Elevated C-reactive protein (CRP) levels.

  2. Increased platelet aggregation rate.

  3. Elevated interleukin-1β (IL-1β).

  4. Elevated interleukin-6 (IL-6).

  5. Elevated cardiac troponin levels.

  6. Elevated fibrinogen levels.

Diagnosis can be established if any of the following criteria are met: ① 1 mandatory indicator plus at least 1 primary macro-indicator, or 2 secondary macro-indicators plus at least 1 laboratory indicator; ② 1 mandatory indicator plus at least 1 primary macro-indicator plus at least 1 secondary macro-indicator.