Table 3.
RRs of Breast and Ovarian Cancer in Mutation Carriers
|
RRa (95% CI) of Cancerfor Carriers of Mutations in |
||||
|
BRCA1 |
BRCA2 |
|||
| Age Group | BreastCancer | OvarianCancer | BreastCancer | OvarianCancer |
| 20–29 years | 17 (4.2–71) | 1.0 | 19 (4.5–81) | 1.0 |
| 30–39 years | 33 (23–49) | 49 (21–111) | 16 (9.3–29) | 1.0 |
| 40–49 years | 32 (24–43) | 68 (42–111) | 9.9 (6.1–16) | 6.3 (1.4–28) |
| 50–59 years | 18 (11–30) | 31 (14–66) | 12 (7.4–19) | 19 (9.0–41) |
| 60–69 years | 14 (6.3–31) | 50 (22–114) | 11 (6.3–20) | 8.4 (2.2–32) |
a
As compared to incidences for England and Wales in 1973–77.