Figure 3.

Stable inter- and intrachromosomal aberrations in Mayak plutonium workers (pseudocolor images). The panels correspond to the schematics in figure 1. a, Interchromosomal aberration (simple translocation) (white arrows), detected using mFISH. b–d, Intrachromosomal aberrations (gray arrows) in chromosome 5 detected using mBAND, showing centromere. Left chromosome in each pair is normal; right chromosome shows aberration. b, Interarm aberration (pericentric inversion), showing the region of the chromosome that was inverted (yellow arrows). c, Intrachromosomal intra-arm aberration (paracentric inversion), showing the region of the chromosome that was inverted (yellow arrows). d, Intrachromosomal intra-arm aberration (intra-arm deletion), showing the region of the arm that was deleted (red arrows).