Table 3.
Molecular IL4R Haplotypes (Complex Alleles) in Filipino Patients with T1D and Controls
|
Frequency in |
||||
| Seven-SNPHaplotype | Controls(N=188)c | Patients(N=178)c | χ2 Pa | ORb (95% CI) |
| CAGTTAT | 70.7 | 77.0 | .49 | 1.38 (.9–2.2) |
| CCTCCGT | 15.4 | 6.7 | .005 | .4 (.2–.8) |
| GAGTTAT | 1.1 | 0 | .50 | .51 (.0–5.8) |
| CAGTTGT | 7.4 | 11.2 | .23 | 1.57 (.8–3.2) |
| CCGCCGT | 3.2 | 5.1 | .38 | 1.62 (.6–4.6) |
| CCTTTGT | 1.6 | 0 | .27 | .35 (.0–3.5) |
| CCTGTAT | .5 | 0 | .98 | 1.12 (.0–15.8) |
| Total (6 df) | .08 | |||
a
The value in boldface italic type is a nominally significant P value (P<.05).
b
Where the frequency in patients was 0, the ORs have been computed under the assumption that a single patient sample carried the haplotype.
c
Sample size (N) refers to the number of chromosomes.