Table 1.

Demographic Information and LOD Scores for Families with Verified PD

	No. of				LOD Score
Sample	Families	SiblingPairs	% Male	Mean ± SDAge at Onset(years)	Including Familieswith parkin Mutations	Excluding Familieswith parkin Mutations
Original	104	116	61	60.4 ± 11.8	3.05a	1.87a
Expanded	150	170	60	60.0 ± 12.1	3.51a	2.47a
Strong family history	65	77	57	58.0 ± 12.2	5.14b	4.12b

^aNonparametric LOD scores computed with Mapmaker/Sibs.

^bParametric LOD scores computed using an autosomal dominant model with 80% penetrance, 0.005 disease allele frequency, and a 3% phenocopy rate.