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. 2025 Feb 7;5(2):267–276. doi: 10.1158/2767-9764.CRC-24-0561

Table 3.

Results from the PROC NLIN model for the GLAND.

Variable Estimate 95% CI LL 95% CI UL P value
FFTP, +1 year
≤25.7 −0.99% −2.96% 1.01% 0.33
>25.7 1.17% 0.20% 2.46% 0.041
Age at MBD measurement, +1 year −1.15% −1.69% −0.61% <0.0001
Age at menarche, +1 year 2.48% 0.43% 4.57% 0.017
Use of a contraceptive pill, yes compared with no −12.24% −20.90% −2.63% 0.014
Use of hormones during menopause, yes compared with no 8.13% 0.54% 16.30% 0.035
Current BMI (kg/m2)
 Underweight and normal Referent
 Overweight −38.49% −42.28% −34.43% <0.0001
 Obese −58.48% −61.64% −55.04% <0.0001
Number of live-born children
 1 child Referent
 2 children −3.55% −10.68% 4.15% 0.363
 3 or more children −9.01% −15.80% −1.68% 0.017

Multiplicative estimates provided are calculated according to eβ for the given unit change.

The multivariate PLR model was adjusted for a priori chosen variables: age at menarche, ever use of OC, ever use of HRT, age at screening, number of live-born children, and current BMI.

Abbreviations: LL, lower limit; UL, upper limit.