Figure 7.

Dendrogram reflecting genetic heterogeneity of cystic fibrosis haplotypes. a, Hierarchical agglomerative clustering of haplotypes, based on a similarity measure defined by the number of times each pair of haplotypes was assigned to the same cluster. b, Posterior mean estimates of Pr(y_i=1)=Φ(γ_ci) (where Φ(·) denotes a standard normal cdf) for haplotype h, arranged in the sequence given in panel a. The darkest bars indicate haplotypes known to contain the ΔF₅₀₈ mutation, the lighter bars indicate case haplotypes, and the lightest bars indicate control haplotypes.