Fig. 3.

a Distribution of changes of DEPs. Volcano plot showed the distribution of DEPs after silencing CEMIP on H446 cells, DEPs located away from two vertical dash lines indicated their expressed fold change were either higher or lower the cut-off value among total expressed change of DEPs. Among them, the pink pots beyond the horizontal dash line presented that their changes also met statistical threshold where p value ≤ 0.05. Bar chart located below this volcano plot briefly summarized the rule of distributed DEPs due to expression changes. b The identified DEPs was hierarchical clustered DEPs whose change fold over 1.2 with statistic significance. The result was displayed as Heat-map. Red cubes indicated up-regulated one while blue cube meant down-regulated one