Table 2.
Univariate and multivariate analyses of PET parameters associated with pN +
18F–FDG PET/CT parameters | Univariate | Multivariate | ||||
---|---|---|---|---|---|---|
ORa | 95% CI | Pa | ORa | 95% CI | Pa | |
SUVmax > 5.3 | 2.32 | 0.99–5.40 | 0.052 | 1.28 | 0.43–3.27 | 0.544 |
SUVpeak > 5.1 | 2.19 | 0.90–5.33 | 0.082 | 1.14 | 0.96–3.30 | 0.541 |
SUVmean > 3.5 | 2.39 | 1.00–5.73 | 0.050 | 1.38 | 0.84–3.21 | 0.240 |
MTV > 6.6 mL | 2.86 | 1.18–6.94 | 0.020* | 2.72 | 1.07–7.78 | 0.037* |
TLG > 24.0 g | 2.69 | 1.11–6.49 | 0.028* | 2.61 | 1.04–6.55 | 0.044* |
CI confidence interval; 18F-FDG 18F-fluorodeoxyglucose; MTV metabolic tumour volume; OR odds ratio; PET/CT positron emission tomography/computed tomography; pN + pathological neck–lymph–node positivity; SUV standardized uptake value; TLG total lesion glycolysis
aBinary logistic regression analyses; multivariate analyses were adjusted for age, histological differentiation, lymphovascular invasion, and T classification, *P < 0.05 (see Supplementary Table S1)