Table 3.
Multivariate analyses of PET parameters associated with survival
18F–FDG PET/CT parameters | Overall survival | Disease-free survival | ||||
---|---|---|---|---|---|---|
HRa | 95% CI | Pa | HRa | 95% CI | Pa | |
SUVmax > 5.0 | 3.44 | 1.01–11.71 | 0.048* | 1.53 | 0.65–3.61 | 0.336 |
SUVpeak > 3.5 | 3.59 | 0.98–16.78 | 0.051 | 1.47 | 0.60–3.62 | 0.405 |
SUVmean > 3.1 | 2.41 | 0.98–13.96 | 0.054 | 1.80 | 0.75–4.34 | 0.188 |
MTV > 2.9 mL | 3.16 | 0.82–12.25 | 0.096 | 1.13 | 0.47–2.75 | 0.784 |
TLG > 9.3 g | 5.74 | 1.20–27.44 | 0.029* | 1.54 | 1.62–3.79 | 0.352 |
CI confidence interval; 18F-FDG 18F-fluorodeoxyglucose; HR hazard ratio; MTV metabolic tumour volume; PET/CT positron emission tomography/computed tomography; SUV standardized uptake value; TLG total lesion glycolysis
aMultivariate Cox proportional hazard regression analyses were adjusted for invasion depth, lymphovascular invasion, and T and N classifications for overall survival, invasion depth, lymphovascular invasion, and T classification for disease-free survival, *P < 0.05 (see Supplementary Table S2)