Table 2.

Subgroup analysis.

Subgroup	ALT				AST				GGT
	Study	SMD [95%CI]	p value	I 2	Study	SMD [95%CI]	p value	I 2	Study	SMD [95%CI]	p value	I 2
Total	9	−0.15 [−0.45, 0.15]	0.33	62%	8	−0.29 [−0.48, −0.10]	0.003	10%	8	−0.07 [−0.26, 0.12]	0.46	30%
Dose
≥2000mg	5	−0.06 [−0.57, 0.44]	0.8	73%	4	-0.10 [−0.37, 0.17]	0.45	0%	4	0.18 [−0.09, 0.45]	0.2	0%
<2000mg	4	−0.27 [−0.61, 0.07]	0.12	38%	4	−0.46 [−0.72, −0.20]	0.0006	0%	4	−0.31 [−0.57, −0.04]	0.02	0%
Time of duration
>12 weeks	5	−0.50 [−0.74, −0.26]	<0.0001	0%	4	−0.46 [−0.71, −0.20]	0.0004	0%	4	−0.24 [−0.50, 0.01]	0.06	0%
≤12 weeks	4	0.23 [−0.05, 0.51]	0.1	0%	4	−0.08 [−0.36, 0.20]	0.56	0%	4	0.14 [−0.14, 0.42]	0.33	16%