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. 2025 Jan 27;122(5):e2401232121. doi: 10.1073/pnas.2401232121

Table 1.

The main problems with the current review system and some of their potential solutions

Category Problems Potential Solution Advantages Disadvantages
Quality Lack of reviewers Monetary compensation More reward Only wealthy publishers can afford it
Preprint peer review

Large public reviewer pool

Timely dissemination

Less publication bias

Rare engagement of the public

Misinformation from preprints

Unclear impact of bias

Improved recruitment

Various resources

Crowdsourcing methods

Need validation of benefits
AI-assisted reviews Massive workforce

Questionable quality

Requires human validation

Lack of qualified reviewers Reviewer training

Better preparation

Standardization

Requires resources

Standardization

Insufficient scrutiny fueling irreproducibility

More reviewers

Open and transparent reviews

More thorough review

More information

Better documentation

Slower process

Variable implementation

Hard to reject papers

Increased specialization Checklists (Ensure that important topics are covered) Standardization Unproven effectiveness
Signed reviews (one can see which specialization was covered in the review)

Higher quality

Fewer unprofessional comments

Conflicts identified

Less critical reviews

Fear of retaliation

Actual retaliation

Predatory journals No review or rudimentary review

Transparent editorial process

+ Signed reviews,

Open and transparent reviews

Clarity how decisions are made Uncertainty about best practices
Biases Bias for or against authors, topics, methods, groups, institutions, countries, arguments, ideas Double-blind peer review Reduced biases

Possibly more critical reviews

Often hard to achieve

Publishing reviews

+ Signed reviews,

Open and transparent reviews, Reviewer training

More transparency Possibly less critical reviews
Poor reliability Limited agreement and frequent disagreement between reviewers Focus revisions on points where reviewers agree, and where they have special expertise Higher reliability Difficulty understanding what drives (dis)agreement between reviewers
Lack of evidence for deciding how to improve the system

Empirical test and

randomized trials

More rigorous evidence

Relatively few examples

Difficult to implement

Not easy to perform in real world

Listed advantages and disadvantages correspond to the solutions in bold.