Table 3.
Features distinguishing gestational transient thyrotoxicosis from Graves’ disease in patients presenting with thyrotoxicosis in the first trimester of pregnancy.
Feature | GTT | Graves’ disease |
---|---|---|
Symptoms of thyrotoxicosis BEFORE pregnancy | No | Often |
Symptoms of hyperemesis gravidarum (nausea/vomiting) | Often | Usually not present |
Personal of family history of thyroid disease | Usually absent | Often present |
Presence of goitre | No/small | Diffuse goitre may be present |
Signs of thyroid eye disease | No | May be present |
fT3 concentration | Usually normal or mildly raised | Raised |
TRAb concentration | Normal | Raised |