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. 2025 Jan 30;122(5):e2409541122. doi: 10.1073/pnas.2409541122

Fig. 2.

Fig. 2.

The impact of new-cue (zinc) adaptation on past-cue (salt) plasticity. (A) Total number of salt-induced differentially expressed (DE) genes in each population and those genes with the same direction of expression change in both coasts/both mines (Coast-B/Mine-B). The horizontal line denotes the proportion of shred genes expected by chance. (B) PCA of variance-stabilized transformed counts of 30,714 genes in each population in control and salt treatments. (C) Bubble plot showing the z-score of coastal and mine genes differentially expressed in salt within significantly enriched GO categories (n up-regulated – n down-regulated/total n in each GO category) against the negative log-transformed P-value for each GO term. 1.0 = 100% up-regulated genes, −1.0 = 100% down-regulated genes, 0.0 = 50% up-/down-regulated genes. Bubbles scale with the number of genes in each GO category and colors represent sets of broader common functions. The 14 common significant GO terms are shown with white outlined diamonds.