Table 4.
Univariate and multivariate analysis of combined status of ERG/PTEN in relation to biochemical recurrence
| Variables | OR | 95% CI | p value |
|---|---|---|---|
| Univariate analysis of combined status of ERG/PTEN in relation to biochemical recurrence | |||
| Combined PTEN and ERG (PTEN pos and ERG neg) | |||
| PTEN neg and ERG pos | 2.831 | 1.10–7.26 | 0.03 |
| PTEN neg and ERG neg | 1.17 | 0.46–2.94 | 0.74 |
| PTEN pos and ERG pos | 1.41 | 0.68–2.92 | 0.35 |
| Multivariate analysis of key pathological parameters and combined ERG/PTEN in relation to biochemical recurrence | |||
| Combined PTEN and ERG (PTEN pos and ERG neg) | |||
| PTEN neg and ERG pos | 2.68 | 0.98–7.33 | 0.05 |
| PTEN neg and ERG neg | 1.34 | 0.50–3.58 | 0.56 |
| PTEN pos and ERG pos | 1.08 | 0.49–2.35 | 0.85 |
| (GG4-5) Gleason score > 7 | |||
| (GG1-3) Gleason score ≤ 7 | 0.31 | 0.14–0.72 | 0.006 |
| Pathology stage (pT2) | |||
| pT3 | 1.79 | 0.89–3.60 | 0.10 |
| Surgical margin neg | |||
| Surgical margin pos | 2.20 | 1.13–4.27 | 0.02 |