Table 2.

Mean change in DLQI scores (baseline to end of study) for responders and non-responders as assessed by patient-reported pruritus severity score

	Baseline		End of Study		Mean Change in DLQI*
	Responder Mean (SD)	Non-Responder Mean (SD)	Responder Mean (SD)	Non-Responder Mean (SD)	Responder Mean (SD)	Non-Responder Mean (SD)
Study A (N = 310)	9.39 (5.56)	9.33 (6.35)	2.33 (3.14)	5.48 (5.53)	-7.06 (5.95)	-3.85 (5.30)
Study B (N = 352)	9.13 (5.38)	9.10 (5.72)	2.18 (2.89)	5.13 (4.99)	-6.94 (5.32)	-3.97 (5.79)

*End of study minus baseline