Table 3.
Characteristics of patients with lung cancer or second lung cancers after PSM analysis
| Lung cancer | Second lung cancer | p value | |
|---|---|---|---|
| n = 165 (%) | n = 166 (%) | ||
| Gender | |||
| Male | 19 (11.5) | 47 (28.3) | < 0.001 |
| Female | 146 (88.5) | 119 (71.7) | |
| Operation | |||
| Anatomic resection | 108 (65.5) | 95 (57.2) | 0.143 |
| Sublobar resection | 57 (34.5) | 71 (42.8) | |
| Differentiation | |||
| Good | 88 (53.3) | 77 (46.4) | 0.362 |
| Moderate | 60 (36.4) | 73 (44.0) | |
| Poor | 17 (10.3) | 16 (9.6) | |
| EGFR gene status | |||
| Wild-type | 39 (23.6) | 48 (28.9) | 0.253 |
| Mutation | 54 (43.6) | 60 (36.1) | |
| Non-test | 72 (32.7) | 58 (34.9) | |
| N Status | |||
| N0 | 149 (90.3) | 150 (90.4) | 0.558 |
| N1 | 5 (3.0) | 8 (4.8) | |
| N2 | 11 (6.7) | 8 (4.8) | |
| Histological type | |||
| Adenocarcinoma | 152 (92.1) | 152 (91.6) | 0.628 |
| Squamous cell carcinoma (SCC) | 6 (3.6) | 9 (5.4) | |
| Others | 7 (4.2) | 5 (3.0) | |
| Performance status (PS) | |||
| 0 | 92 (55.8) | 107 (64.5) | 0.219 |
| 1 | 56 (33.9) | 50 (30.1) | |
| 2 | 16 (9.7) | 9 (5.4) | |
| 3 | 1 (0.6) | 0 (0) | |
| Location | |||
| Central | 72 (43.6) | 87 (52.4) | 0.124 |
| Peripheral | 93 (56.4) | 79 (47.6) | |
| Adjuvant chemotherapy | |||
| Yes | 52 (31.5) | 45 (27.1) | 0.400 |
| No | 113 (68.5) | 121 (72.9) | |
| Adjuvant radiotherapy | |||
| Yes | 12 (7.3) | 10 (6.0) | 0.666 |
| No | 153 (92.7) | 156 (94.0) | |
| Smoking | |||
| Yes | 22 (13.3) | 24 (14.5) | 0.166 |
| No | 139 (84.2) | 131 (78.9) | |
| Ex-smoker | 4 (2.4) | 11 (6.6) | |
| Lymphovascular space invasion (LVSI) | |||
| Absent | 152 (92.1) | 154 (93.3) | 0.833 |
| Present | 13 (7.9) | 11 (6.7) | |
| Visceral pleural invasion (VPI) | |||
| Absent | 163 (98.8) | 158 (95.8) | 0.174 |
| Present | 2 (1.2) | 7 (4.2) | |
| Stage | |||
| 0 | 2 (1.2) | 7 (4.2) | 0.283 |
| I | 139 (84.2) | 135 (81.3) | |
| II | 5 (3.0) | 9 (5.4) | |
| III | 16 (9.7) | 11 (6.6) | |
| IV | 3 (1.8) | 4 (2.4) | |
Statistical significance is defined as p < 0.05 (Bold)