Figure 4.

Transcriptomic and proteomic analyses of EMT. (a) Overview of the EMTome for sequencing: (i) schematic of the EMTome database, and (ii) workflow to generate the EMT-signature score. Reproduced with permission from Ref. [63]. Copyright 2020, Springer Nature. (b) Mapping the EMT process based on mass cytometry data: (i) workflow of cells receiving TGF-β treatment time-course; (ii) a reference map of EMT-MET states; (iii) expression profiles of six clustering markers in lung cancer cell lines (HCC827) visualized on the EMT-MET reference map. Reproduced with permission from Ref. [65]. Copyright 2019, Springer Nature.