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. 2003 Oct 14;73(5):1073–1081. doi: 10.1086/379154

Figure 1.

Figure 1

Yin yang haplotype patterns of a 500-kb IBD susceptible locus in 5q31, with 85 SNPs that have minor-allele frequency ⩾10%. The haplotypes were derived from genotypes of 389 individuals. A, Haplotype patterns in a 98-kb region, with 24 SNPs that exhibit the yin yang pattern. The major and minor SNP alleles are indicated in blackened and unblackened circles, respectively. The yin yang haplotypes are grouped together and highlighted in gray. The haplotypes in this region are sorted in descending order of their population frequencies, and the red, blue, and black lines represent haplotypes with population frequencies of ⩾15%, ⩾5%, and ⩾3%, respectively. B, Yin yang haplotype structure of the entire locus. The SNPs are displayed in diamonds and grouped into boxes that represent yin yang haplotype regions. The orange lines above the boxes indicate the haplotype blocks identified by Daly et al. (2001). Section A is an enlarged view of the region in section B that is set off in the rectangle. The yin yang regions in this locus contain 93% of the SNPs and cover 88% of the genomic region, in terms of physical distance. The figure was modified from a screen shot generated by the HapScope viewer (Zhang et al. 2002).