Table.
Average DTI Parameters for Visual Pathways (± Standard Deviation Along Each Fiber)
| Optic tract | Optic Radiation | Foveal Fibers | Parafoveal Fibers | Occipito-callosal Fibers | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| FA | AD | RD | FA | AD | RD | FA | AD | RD | FA | AD | RD | FA | AD | RD | |
| Patient 1 | |||||||||||||||
| Before treatment | 0.328 ±0.034 | 1.685 ±0.027 | 0.987 ±0.46 | 0.394 ±0.050 | 2.035 ±0.095 | 1.073 ±0.099 | 0.372 ±0.063 | 1.944 ±0.093 | 1.074 ±0.130 | 0.398 ±0.056 | 2.055 ±0.116 | 1.069 ±0.098 | 0.435 ±0.092 | 2.083 ±0.181 | 1.006 ±0.173 |
| After treatment | 0.391 ±0.03 | 1.651 ±0.046 | 0.860 ±0.46 | 0.376 ±0.047 | 2.018 ±0.132 | 1.100 ±0.077 | 0.380 ±0.054 | 1.948 ±0.117 | 1.066 ±0.085 | 0.374 ±0.048 | 2.033 ±0.141 | 1.109 ±0.078 | 0.466 ±0.134 | 2.070 ±0.210 | 0.954 ±0.249 |
| Patient 2 | |||||||||||||||
| Before treatment | 0.365 ±0.051 | 1.526 ±0.082 | 0.848 ±0.089 | 0.388 ±0.070 | 2.119 ±0.180 | 1.119 ±0.101 | 0.386 ±0.057 | 2.124 ±0.147 | 1.122 ±0.115 | 0.385 ±0.071 | 2.118 ±0.197 | 1.125 ±0.093 | 0.382 ±0.110 | 2.087 ±0.192 | 1.125 ±0.179 |
| After treatment | 0.389 ±0.067 | 1.480 ±0.137 | 0.792 ±0.162 | 0.401 ±0.058 | 2.103 ±0.123 | 1.086 ±0.112 | 0.371 ±0.086 | 2.092 ±0.160 | 1.145 ±0.141 | 0.377 ±0.065 | 2.143 ±0.164 | 1.157 ±0.120 | 0.362 ±0.117 | 2.099 ±0.247 | 1.198 ±0.250 |
| Patient 3 | |||||||||||||||
| Before treatment | 0.343 ±0.04 | 1.405 ±0.071 | 0.800 ±0.058 | 0.402 ±0.044 | 1.931 ±0.115 | 1.010 ±0.095 | 0.342 ±0.074 | 1.944 ±0.112 | 1.131 ±0.106 | 0.388 ±0.053 | 1.828 ±0.117 | 0.995 ±0.063 | 0.345 ±0.178 | 1.905 ±0.221 | 1.118 ±0.301 |
| After treatment | 0.260 ±0.042 | 1.556 ±0.062 | 1.031 ±0.096 | 0.431 ±0.049 | 2.050 ±0.135 | 1.000 ±0.077 | 0.451 ±0.082 | 1.990 ±0.149 | 0.939 ±0.111 | 0.433 ±0.050 | 2.029 ±0.115 | 0.989 ±0.086 | 0.470 ±0.121 | 1.985 ±0.206 | 0.904 ±0.203 |
| Control (SD among controls) | 0.355 (0.026) | 1.631 (0.150) | 0.917 (0.094) | 0.407 (0.036) | 1.985 (0.101) | 1.018 (0.063) | 0.411 (0.032) | 2.009 (0.103) | 1.024 (0.072) | 0.412 (0.042) | 2.004 (0.106) | 1.020 (0.071) | 0.495 (0.020) | 2.018 (0.061) | 0.865 (0.052) |
| Mann-Whitney–derived P value for pretreatment comparison | 0.559 | 0.359 | 0.559 | 0.793 | 0.487 | 0.254 | 0.048a | 0.84 | 0.07 | 0.536 | 0.84 | 0.448 | 0.002b | 0.875 | 0.002b |
| Mann-Whitney–derived P value for post-treatment comparison | 0.712 | 0.359 | 0.793 | 0.875 | 0.138 | 0.303 | 0.734 | 0.945 | 0.536 | 0.448 | 0.295 | 0.233 | 0.014a | 0.487 | 0.033a |
Diffusion parameters of each fiber for patients and controls. Averages and standard deviations along fibers are included for each patient and controls. P values were derived through the Mann–Whitney test comparing patients and controls.
P < 0.05.
P < 0.01.