Table 2. Laboratory findings for controls, all patients with CO poisoning, and those with 1 month follow-up.
Comparisons among the control group, all patients with CO exposure, patients with follow-up results at 1 month and GDS = 1, and those where 1-month GDS was >1. Rows demonstrate age, % male, plasma GSN, flow cytometry results including MPs/μl, % of MPs expressing various protein markers specific to different cells including neutrophils (CD66b), endothelium (CD146), platelets (CD41a), and neutrophils (PMN) % expressing protein values above a minimum threshold for CD18, MPO, pGSN, and CD41a [indicative of platelet-neutrophil interaction as described previously (15)]. Data are mean ± SD. Statistical comparisons were made between control and all 150 patients with CO poisoning and values with P < 0.05 (t test) indicated by +, and between patients with good outcome versus neurological sequelae with P < 0.05 indicated by *. NS, not significant.
| Control (n = 150) | All CO (n = 150) | CO-good (n = 65) | CO-DNS (n = 33) | |
|---|---|---|---|---|
| Age (years) | 45.3 ± 16.3 | 47.9 ± 17.2 NS | 44.4 ± 15.0 | 54.4 ± 19.4* |
| % Male | 65.3 ± 47.8 | 65.3 ± 47.8 NS | 63.2 ± 48.6 | 50.0 ± 50.8 |
| pGSN (μg/ml) | 178.1 ± 161.5 | 11.6 ± 11.7+ | 13.4 ± 16.4 | 11.6 ± 6.8 |
| MPs/μl | 1100 ± 447 | 1423 ± 489+ | 1485 ± 560 | 1431 ± 435 |
| % CD66b | 12.6 ± 5.8 | 16.6 ± 7.3+ | 17.2 ± 0.9 | 16.3 ± 6.7 |
| % CD146 | 26.4 ± 10.6 | 26.7 ± 8.8+ | 27.0 ± 9.8 | 24.3 ± 7.5 |
| % TSP | 11.3 ± 4.5 | 13.6 ± 6.1+ | 13.6 ± 5.8 | 14.0 ± 6.9 |
| % CD41 | 6.8 ± 2.4 | 7.6 ± 7.6 NS | 7.8 ± 7.8 | 7.0 ± 2.1 |
| % TMEM | 29.4 ± 4.5 | 31.5 ± 4.9+ | 32.5 ± 4.7 | 30.5 ± 6.4 |
| % F-actin | 17.1 ± 2.0 | 20.3 ± 9.0 | 20.1 ± 4.5 | 20.3 ± 5.6 |
| PMN % CD18 | 4.2 ± 5.2 | 7.2 ± 4.7+ | 7.2 ± 5.0 | 6.6 ± 3.2 |
| PMN % MPO | 4.2 ± 3.8 | 8.4 ± 4.7+ | 9.8 ± 5.0 | 9.0 ± 4.4 |
| PMN % CD41 | 5.9 ± 4.2 | 9.6 ± 4.4+ | 9.7 ± 3.8 | 10.2 ± 5.3 |
| PMN % pGSN | 5.0 ± 2.0 | 4.5 ± 2.9 NS | 5.2 ± 3.3 | 4.6 ± 2.8 |